University of California, Riverside

Division of Biomedical Sciences



Biomedical Sciences Faculty


Tara M. Nordgren

Assistant Professor of Biomedical Sciences

Tara M. Nordgren

University of California, Riverside
Riverside, CA 92521

Tel: (951) 827-3148
E-mail: tara.nordgren@medsch.ucr.edu
Office: 211 School of Medicine Research Building

Education and Training

  • B.S. Biology, George Mason University, Fairfax, Virginia
  • Ph.D. Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska
  • Postdoctoral, Internal Medicine—Pulmonary, Critical Care, Sleep and Allergy Division, University of Nebraska Medical Center, Omaha, Nebraska

Research Summary

My research interests involve investigating the role of omega-3 fatty acid-derived lipid mediators in inflammation resolution. I have a K99/R00 grant through NIEHS to study how omega-3 fatty acids serve as substrates for the biosynthesis of pro-resolving lipid mediators during lung inflammation caused by environmental exposures. My long-term research goals include identifying the mechanisms underlying these bioactive lipids and harnessing their pro-resolution properties to prevent inflammatory diseases.

Awards

  • Environmental Occupational and Population Health Abstract Scholarship, American Thoracic Society, 2017.
  • Postdoctoral Fellow Research Award, UNMC Department of Internal Medicine, 2014.
  • Postdoctoral Pathway to Independence Award, UNMC Department of Internal Medicine, 2013.
  • First place oral presentation award - Graduate Student/Resident category, 41st Annual Midwest Student Biomedical Research Forum, 2010.
  • First place oral presentation award - Graduate Student/Resident category, 40th Annual Midwest Student Biomedical Research Forum, 2009.

Selected Publications

  • Tara M. Nordgren, Elizabeth Lyden, Ann Anderson-Berry, Corrine Hanson. Omega-3 fatty acid Intake of pregnant women and women of childbearing age in the United States: potential for deficiency? Nutrients 2017, 9(3).
  • Kristi Warren, Todd A. Wyatt, Debra J. Romberger, William W. West, Amy Nelson, Tara M. Nordgren, Elizabeth Staab, Art J. Heires, Jill A. Poole. Post-injury homeostasis and resolution response to repetitive inhalation exposure to agriculture organic dust in mice. Safety 2017, 3(1): 10.
  • Viswanathan Saraswathi, Curtis Perriotte-Olson, Murali Ganesan, Cyrus V Desouza, Yazen Alnouti, Michael J Duryee, Geoffrey M Thiele, Tara M Nordgren, Dahn L Clemens. Combination of dietary n-3 fatty acids and a cyclooxygenase I inhibitor attenuates non-alcoholic fatty liver disease in mice. J Nutr Biochem 2017; 42:149-159.
  • Todd A. Wyatt, Kerry Canady, Art J. Heires, Jill A. Poole, Kristina L. Bailey, Tara M. Nordgren, and Debra J. Romberger. Alcohol inhibits organic dust-induced ICAM-1 expression on bronchial epithelial cells. Safety 2017; 3(1): 5.
  • Debra J. Romberger, Art J. Heires, Tara M. Nordgren, Jill A. Poole, Myron L. Toews, William W. West, and Todd A. Wyatt. Beta-2 agonists attenuate organic dust-induced lung inflammation. Am J Physiol Lung Cell Mol Physiol, 2016; 311 (1): L101-10.
  • Tara M. Nordgren and Kristina L. Bailey. Pulmonary Health Effects of Agriculture.Curr Opin Pulm Med 2016 Mar; 22(2): 144-9 (Review).
  • Carresse L. Gerald, Debra J. Romberger, Jane M. DeVasure, Rohan Khazanchi, Tara M. Nordgren, Art J. Heires, Joseph H. Sisson, Todd A. Wyatt. Alcohol decreases organic dust-stimulated airway epithelial TNF-alpha through a nitric oxide and PKA-mediated inhibition of TACE. Alcohol Clin Exp Res 2016 Feb; 40(2): 273-83.
  • Debra J. Romberger, Art J. Heires, Tara M. Nordgren, Chelsea P. Souder, William West, Xiang-de Liu, Jill A. Poole, Myron Toews, and Todd A. Wyatt. Proteases in agricultural dust induce lung inflammation through PAR-1 and PAR-2 activation. Am J Physiol Lung Cell Mol Physiol 2015; 309(4): L388-399.
  • Tara M Nordgren, Chris D Bauer, Art J Heires, Jill A Poole, Todd A Wyatt, William W West, and Debra J Romberger. Maresin-1 reduces airway inflammation associated with acute and repetitive exposures to organic dust. Transl Res 2015; 166(1): 57-69.
  • Tara M Nordgren, Taylor D Friemel, Arthur J Heires, Jill A Poole, Todd A Wyatt and Debra J Romberger. The omega-3 fatty acid docosahexaenoic acid attenuates organic dust-induced airway inflammation. Nutrients 2014; 6(12): 5434-5452.
  • Todd A Wyatt, Jill A Poole, Tara M Nordgren, Jane M DeVasure, Art J Heires, Kristina L Bailey, and Debra J Romberger. Cyclic AMP-dependent protein kinase activation decreases cytokine release in bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol 2014; 307(8): L643-651.
  • Amit K Mittal, Nagendra K Chaturvedi, Karan J Rai, Christine E Gilling, Tara M Nordgren, Margaret Moragues, Runqing Lu, Rene Opavsky, Greg R Bociek, Dennis D Weisenburger, Javeed Iqbal, Shantaram S Joshi. Chronic lymphocytic leukemia cells in lymph node microenvironment depict molecular signature associated with an aggressive disease. Mol Med 2014; 20(1): 290-301.
  • Tara M Nordgren, Todd A Wyatt, Jenea Sweeter, Kristina L Bailey, Jill A Poole, Joseph H Sisson, and Debra J Romberger. Motile cilia harbor serum response factor as a mechanism of environment sensing and injury response in the airway. Am J Physiol Lung Cell Mol Physiol 2014; 306(9): L829-839.
  • Haley L Peters, Ying Yan, Tara M Nordgren, Christine E Cutucache, Shantaram S Joshi, and Joyce C Solheim. Amyloid precursor-like protein 2 suppresses irradiation-induced apoptosis in Ewing sarcoma cells and is elevated in immune-evasive Ewing sarcoma cells.Cancer Biol Ther. 2013; 14(8): 752-760.
  • Tara M Nordgren, Art J Heires, Todd A Wyatt, Jill A Poole, Tricia D LeVan, D Roselyn Cerutis, and Debra J Romberger. Maresin-1 reduces the pro-inflammatory response of bronchial epithelial cells to organic dust.Respir Res 2013; 14: 51. Given “Highly Accessed” designation by BioMed Central.
  • Adam K Ahrens, Nagendra Chaturvedi, Ashima Shukla, Tara M Nordgren, Ganapati V Hegde, Julie M Vose, and Shantaram S Joshi. Polo-like-kinase 1: a novel target for the treatment of therapy-resistant mantle cell lymphoma.Lymphoma vol. 2013, Article ID 782903, 10 pages.
  • Adam K Ahrens, Nagendra Chaturvedi, Tara M Nordgren, Shantaram S Joshi. Establishment and characterization of therapy-resistant mantle cell lymphoma cell lines derived from different tissue sites. Leuk Lymphoma 2012; 53(11): 2269-2278.
  • Ganapati V Hegde, Tara M Nordgren, Corey M Munger, Amit K Mittal, Philip J Bierman, Dennis D Weisenburger, Julie M Vose, J Graham Sharp, Shantaram, S Joshi. Novel Therapy for Therapy-Resistant Mantle Cell Lymphoma: Multipronged Approach with Targeting Hedgehog Signaling. Int J Cancer 2012; 131(12): 2951-2960.
  • Tara M Nordgren, Ganapati V Hegde, and Shantaram S Joshi.Ritonavir exhibits limited efficacy as a single agent in treating aggressive mantle cell lymphoma. J Cancer Sci Ther 2012; 4(4): 061-068.
  • Gayathri Kollessery** and Tara M Nordgren**, Amit K Mittal, Shantaram S Joshi, Sam D Sanderson. Tumor-specific peptide-based vaccines containing the conformationally biased, response selective C5a agonists EP54 and EP67 protect against aggressive large B cell lymphoma in a syngeneic murine model. Vaccine 2011; 29(35): 5904-5910. **Equally contributing first authors.
  • Tara M Nordgren and Shantaram S Joshi. The Etiology of Chronic Lymphocytic Leukemia: Another Look at the Relationship Between B1 Cells and CLL. Open Leuk J 2010; 3: 69-73 (Review).
  • Ashley D Reynolds, Irena Kadiu, Sanjay K Garg, Jason G Glanzer, Tara M Nordgren, Pawel Ciborowski, Ruma Banerjee, and Howard E Gendelman.  Nitrated alpha-synuclein and microglial neuroregulatory activities.  J Neuroimmune Pharmacol. 2008; 3(2): 59–74.

More Information 

General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

Department Information

Division of Biomedical Sciences
UC Riverside School of Medicine
2608 School of Medicine Education Building

Tel: (951) 827-5470

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